Network Meta-Analysis Ranks Best Non-Drug Sleep Interventions for Older Adults

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TL;DR

CBT-I ranks #1 (PSQI -4.8), combined aerobic+resistance exercise #2 (-3.9), and MBSR #3 (-3.5) for improving sleep in adults 60+, based on 89 RCTs with 7,236 participants.

Background

With over 50% of older adults reporting sleep problems, non-pharmacological interventions are increasingly preferred over sleep medications due to side effect concerns. However, the relative effectiveness of different interventions has been unclear — until now.

Key Findings

The University of Melbourne-led network meta-analysis included 89 RCTs with 7,236 participants aged 60+.

Rank Intervention PSQI Improvement Evidence Quality
1 CBT-I -4.8 High
2 Aerobic + Resistance Exercise -3.9 Moderate-High
3 MBSR -3.5 Moderate
4 Yoga -3.2 Moderate
5 Tai Chi -2.9 Moderate
6 Aerobic Exercise (alone) -2.7 Moderate-High

Differential Effects

  • Sleep onset: CBT-I > Mindfulness > Yoga > Aerobic
  • Sleep maintenance: Combined Exercise > CBT-I > Tai Chi
  • Deep sleep: Aerobic > Yoga > Tai Chi > CBT-I

Clinical Implications

  1. CBT-I as first-line for all insomnia types in older adults
  2. Afternoon exercise (4-6 PM) promotes 18% more deep sleep than morning
  3. Combined interventions yield 1.8× the effect of single approaches

References

  1. [1]https://doi.org/10.1186/s12916-026-04682-6

Frequently Asked Questions

Many digital CBT-I programs (Sleepio, CBT-I Coach) show similar effectiveness. Exercise and mindfulness are excellent alternatives available to most people.

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